PyGUI
A simple API that enables developers to create user interfaces with native elements for Python applications.
Best PyGUI Alternatives & Competitors in 2025
The best PyGUI alternatives based on verified products, community votes, reviews and other factors.
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Open-Source Alternatives.
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wxPython is a GUI toolkit for the Python programming language.
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Design GUI with Python: Python Bindings for Qt
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Monitor all your cloud services with our status page aggregator. IT teams choose IsDown to monitor all their vendors and get alerts whenever an outage occurs. Integration with Datadog, PagerDuty, Slack, Microsoft Teams, and a lot more.
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Pyforms is a Python 3 framework to develop applications capable of executing in 3 diferent environments, Desktop GUI, Terminal and Web.
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Tkinter is a Python wrapper for Tcl/Tk that offers classes to create various graphical user interfaces.
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libavg is a high-level development platform for media-centric applications.
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Open source Python framework for rapid development of applications that make use of innovative user interfaces, such as multi-touch apps. Installation on WindowsInstallation on Windows. Installation; What are wheels .
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Riverbank | Software | PyQt | What is PyQt?
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A simple to use GUI that can create custom GUIs
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Qt for Python - Qt Wiki
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wxWidgets: Cross-Platform GUI Library
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Powerful, flexible and easy to use, Qt will help you not only meet your tight deadline, but also reduce the maintainable code by an astonishing percentage.
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Build beautiful native apps in record time 🚀
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Build cross platform desktop apps with web technologies
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