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wxPython - wxPython is a GUI toolkit for the Python programming language.
PyQt - Riverbank | Software | PyQt | What is PyQt?
QT for Python - Design GUI with Python: Python Bindings for Qt
PySimpleGUI - A simple to use GUI that can create custom GUIs
Pyforms - Pyforms is a Python 3 framework to develop applications capable of executing in 3 diferent environments, Desktop GUI, Terminal and Web.
GTK - GTK+ is a multi-platform toolkit for creating graphical user interfaces.