wxPython
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Qt
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GTK
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MD Python Designer
PyQt
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Tkinter
PyGTK
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PyQt - Riverbank | Software | PyQt | What is PyQt?
MD Python Designer - A drag and drop GUI Designer that uses a combination of Tkinter and its own code.
Kivy - Open source Python framework for rapid development of applications that make use of innovative user interfaces, such as multi-touch apps. Installation on WindowsInstallation on Windows. Installation; What are wheels .
Qt - Powerful, flexible and easy to use, Qt will help you not only meet your tight deadline, but also reduce the maintainable code by an astonishing percentage.
PySimpleGUI - A simple to use GUI that can create custom GUIs
Tkinter - Tkinter is a Python wrapper for Tcl/Tk that offers classes to create various graphical user interfaces.