Tkinter - Tkinter is a Python wrapper for Tcl/Tk that offers classes to create various graphical user interfaces.
wxPython - wxPython is a GUI toolkit for the Python programming language.
PyGUI - A simple API that enables developers to create user interfaces with native elements for Python applications.
Qt - Powerful, flexible and easy to use, Qt will help you not only meet your tight deadline, but also reduce the maintainable code by an astonishing percentage.
Kivy - Open source Python framework for rapid development of applications that make use of innovative user interfaces, such as multi-touch apps. Installation on WindowsInstallation on Windows. Installation; What are wheels .
PyQt - Riverbank | Software | PyQt | What is PyQt?