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PyGUI - A simple API that enables developers to create user interfaces with native elements for Python applications.
PyQt - Riverbank | Software | PyQt | What is PyQt?
wxPython - wxPython is a GUI toolkit for the Python programming language.
PySimpleGUI - A simple to use GUI that can create custom GUIs
Pyforms - Pyforms is a Python 3 framework to develop applications capable of executing in 3 diferent environments, Desktop GUI, Terminal and Web.
Tkinter - Tkinter is a Python wrapper for Tcl/Tk that offers classes to create various graphical user interfaces.