What are some alternatives?
When comparing Cheat Engine and PlayOnLinux, you can also consider the following products
GameGuardian - Play games your way! “GameGuardian” is a game hack/alteration tool.
Proton - Compatibility tool for Steam Play based on Wine and additional components
WeMod - This program allows the user to access multiple trainers and cheats for a lot of games.
CrossOver - Don't buy a Windows license, don't reboot and don't use a Virtual Machine. Try a free trial of CrossOver to run your Windows software on Mac, Linux and Chrome OS.
Cheat Evolution - Cheats, Trainers and Mods for all your games in the Cheat Evolution App!
Wine - Open Source Software for running Windows applications on other operating systems.