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Cheat Engine - Cheat Engine is an open source memory scanner/hex editor/debugger for Windows.
Wine - Open Source Software for running Windows applications on other operating systems.
WeMod - Personalize your gaming experience Thousands of free mods and trainers for your favorite single-player PC games — all in one place.
CodeWeavers CrossOver - Don't buy a Windows license, don't reboot and don't use a Virtual Machine. Try a free trial of CrossOver to run your Windows software on Mac, Linux and Chrome OS.
GameGuardian - Play games your way! “GameGuardian” is a game hack/alteration tool.
WineBottler - WineBottler is an App to manage and wrap your Windows apps into convenient OS X apps.