IDLE
PyCharm
Spyder
iPython
Thonny
PyDev
Wing IDE
PyScripter
GCC C Preprocessor (cpp)
Gema
GNU M4
Filepp
GPP
PP - A generic Preprocessor
preprocess
Perl
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PyCharm - Python & Django IDE with intelligent code completion, on-the-fly error checking, quick-fixes, and much more...
Gema - General purpose text macro processor.
Spyder - The Scientific Python Development Environment
GNU M4 - GNU M4 is an implementation of the m4 macro preprocessor.
iPython - iPython provides a rich toolkit to help you make the most out of using Python interactively.
Filepp - filepp is a generic file preprocessor.