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Maxima - Maxima is a fairly complete computer algebra system written in Lisp with an emphasis on symbolic computation.
Wolfram Mathematica - Mathematica has characterized the cutting edge in specialized processing—and gave the chief calculation environment to a large number of pioneers, instructors, understudies, and others around the globe.
GNU Octave - GNU Octave is a programming language for scientific computing.
QtOctave - QtOctave: a front-end for Octave/un Front-End para Octave
MATLAB - A high-level language and interactive environment for numerical computation, visualization, and programming
Xcos - Xcos is a graphical editor to design hybrid dynamical systems models.