Spine
Synfig Studio
Creature
Spriter Pro by BrashMonkey
Animation Paper
DigiCel FlipBook
Unity 2D
CrazyTalk Animator
assertpy
grappa
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Synfig Studio - Just another WordPress site
grappa - grappa is an declarative, verbose, and expressive assertion library for Python.
Creature - Creature 2D Skeletal and Mesh Animation Tool
Spriter Pro by BrashMonkey - Spriter : an intuitive 2D animation tool for video game makers.
Animation Paper - Animation Paper is a software package for doing 2D animation.
DigiCel FlipBook - Whether you do 2D, 3D or stop motion Animation, DigiCel FlipBook makes animation easier!