Live2D Cubism
Spine
DragonBones
Creature
Synfig Studio
Inochi Creator
VSeeFace
enve
Code Flex
Live2D Cubism
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Spine - Spine is 2D animation software designed specifically for software and game development.
DragonBones - DragonBones is an open source project for 2D skeletal animation.
Creature - Creature 2D Skeletal and Mesh Animation Tool
Synfig Studio - Just another WordPress site
Inochi Creator - Inochi2D Rigging Application
VSeeFace - VSeeFace is a free, highly configurable face and hand tracking VRM and VSFAvatar avatar puppeteering program for virtual youtubers with a focus on robust tracking and high image quality