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Microsoft Office Excel - Microsoft Office Excel is a commercial spreadsheet application.
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LibreOffice - Calc - LibreOffice Calc is the spreadsheet program you've always needed. A fork of OpenOffice.
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Airtable - Airtable works like a spreadsheet but gives you the power of a database to organize anything. Sign up for free.
DataMelt - DataMelt (DMelt), a free mathematics and data-analysis software for scientists, engineers and students.