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Out of Office Email Generator - Personalized, witty OOO replies for guilt-free vacationing.
Horde - Horde Groupware is a free, enterprise ready, browser based collaboration suite.
Rebump - Automatic follow up emails. Keeps on bumping until you get a reply.
Roundcube - Web-based IMAP email client
Cop-Out - The ultimate excuse generator
Mailo - Mailo is an email client where you can send and receive emails to and from anyone with an email address.