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Out of Office Email Generator - Personalized, witty OOO replies for guilt-free vacationing.
HEY - Email at its best, new from Basecamp.
Rebump - Automatic follow up emails. Keeps on bumping until you get a reply.
Horde - Horde Groupware is a free, enterprise ready, browser based collaboration suite.
Excuse generator - Don't want to go to office? They are here to help.
InstAddr - Disposable email address application.