Pygame - Pygame is a set of Python modules designed for writing games.
Blender - Blender is the open source, cross platform suite of tools for 3D creation.
Unigine - Unigine Engine is a proprietary cross-platform middleware, developed by Unigine Corp.
Autodesk 3DS Max - 3ds Max is software for 3D modeling, animation, rendering, and visualization. Create stunning game enrivonments, design visualizations, and virtual reality experiences.
libtwo - All-purpose c++ app prototyping library, focused towards live graphical apps and games
Cinema 4D - Cinema 4D is a 3D modeling, animation, motion graphics and rendering application.