Pygame - Pygame is a set of Python modules designed for writing games.
Blender - Blender is the open source, cross platform suite of tools for 3D creation.
Unigine - Unigine Engine is a proprietary cross-platform middleware, developed by Unigine Corp.
Cinema 4D - Cinema 4D is a 3D modeling, animation, motion graphics and rendering application.
libtwo - All-purpose c++ app prototyping library, focused towards live graphical apps and games
Autodesk Maya - Maya is 3D computer animation software with powerful modeling, rendering, simulation, texturing, and animation tools for artists, modelers, and animators.