Wing Commander: Privateer - Wing Commander: Privateer is a space simulator and adventure game that allows you to build your own story in this dog eat dog universe.
Sins Of A Solar Empire - Sins of a Solar Empire is an Adventure, Strategy, Real-time-strategy, Science-fiction, Exploration, Aliens, Single and Multiplayer Space Simulation developed by Ironclad Games and published by Stardock.
DarkStar One - DarkStar One is targeted on space trading and combat.
Endless Space - Endless Space is an Amazing, Strategy, Science-fiction, Turn-based, Space, Futuristic, Exploration, Co-op, Single and Multiplayer Space Simulation created and published by Amplitude Studios.
Evochron Mercenary - Official Webpage for Evochron Mercenary, a 3D space combat and trader simulation. Screenshots, free demo, forum, cheats, videos, and more.
EVE Online - Player-created empires, player-driven markets, and endless ways to embark on your personal sci-fi adventure.