Sins Of A Solar Empire - Sins of a Solar Empire is an Adventure, Strategy, Real-time-strategy, Science-fiction, Exploration, Aliens, Single and Multiplayer Space Simulation developed by Ironclad Games and published by Stardock.
EVE Online - Player-created empires, player-driven markets, and endless ways to embark on your personal sci-fi adventure.
Stellaris - Stellaris is an Adventure-based, RTS (Real-time Strategy) Space, Sandbox, Sci-Fi, Single and Multiplayer video game created and published by Paradox Interactive.
FreeOrion - FreeOrion is a turn-based space empire and galactic conquest (4X) computer game being designed and...
Star Ruler - Star Ruler is an Action-Adventure, Science-fiction, Real-time Strategy, Space, Strategy, Single and Multiplayer video game developed by Blind Mind Studios and published by IGS.
Planet Capture - Browser-based, sci-fi space RTS game.