AutoHotkey - The ultimate automation scripting language for Windows.
EventGhost - EventGhost is an advanced, easy to use and extensible automation tool for MS Windows.
Pulover’s Macro Creator - Pulover’s Macro Creator is a Free Automation Tool and Script Generator.
Homeseer - HomeSeer presents a revolutionary approach to home automation.
AutoKey - A Python 3 port of AutoKey, the desktop automation utility for Linux and X11.
Home-Assistant.io - Home Assistant is an open-source home automation platform running on Python 3.