MirrorCreator - Upload one file of 400 megs or less to multiple free file hosts -- 14 at most. 25 possible hosts.
Loadpass - Start Uploading Your Files To Multiple File Hosting Sites
DirectMirror - Directmirror.com uploads your file to several free hosting providers.
UploadOnAll - UploadOnAll.Com uploads your files to 10 different Free file hosts. We support Rapidshare, Megaupload, Easy Share, ZShare, DepositFiles, FileFactory, sendspace, NetLoad and many more! You can REMOTE upload from direct URL to file mirrors hosting
MultiUp - Your files will be uploaded on many filehosting websites. MultiUp.org is a file mirror website.
MegaUpper - Upload a file to up to 12 file hosting services with just one click.