MATLAB - A high-level language and interactive environment for numerical computation, visualization, and programming
PTC Mathcad - PTC Mathcad PTC Mathcad is Engineering Math Software That Allows You to Perform, Analyze, and Share Your Most Vital Calculations.
GNU Octave - GNU Octave is a programming language for scientific computing.
SMath Studio - Tiny, powerful, free mathematical program with WYSIWYG editor and complete units of measurements support.
Wolfram Mathematica - Mathematica has characterized the cutting edge in specialized processing—and gave the chief calculation environment to a large number of pioneers, instructors, understudies, and others around the globe.
Miramath - Miramath is an open source project inspired by the MathCad mathematical application.