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Derby.js - MVC framework making it easy to write realtime, collaborative applications that run in both Node.
ExpressJS - Sinatra inspired web development framework for node.js -- insanely fast, flexible, and simple
Ruby on Rails - Ruby on Rails is an open source full-stack web application framework for the Ruby programming...
Koa.js - Next generation web framework for node.js
Django - The Web framework for perfectionists with deadlines
Flask - a microframework for Python based on Werkzeug, Jinja 2 and good intentions.