Twidere - Tired of seeing ads and promotions in your timeline, being disrupted by tweets from bots and people...
Janetter - Janetter is a Twitter client application. Faster, smarter, and more powerful.
Tweetbot - Sync your timeline across your iPhone, iPad, and Mac. Mute tweets by user, hashtag, tweet source, or keywords (including regex). 3rd Party support for image, video, read later, and timeline sync services.
YoruFukurou - YoruFukurou (NightOwl) is a Twitter client for Mac OS X, designed for Twitter addicts.
TweetDeck - TweetDeck is your personal browser for staying in touch with what’s happening now.
Talon for Twitter - Elegantly designed, ad-free Twitter experience for Android