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Janetter - Janetter is a Twitter client application. Faster, smarter, and more powerful.
Tweetbot - Sync your timeline across your iPhone, iPad, and Mac. Mute tweets by user, hashtag, tweet source, or keywords (including regex). 3rd Party support for image, video, read later, and timeline sync services.
YoruFukurou - YoruFukurou (NightOwl) is a Twitter client for Mac OS X, designed for Twitter addicts.
TweetDeck - TweetDeck is your personal browser for staying in touch with what’s happening now.
Tweeticide - Tweeticide – Delete All Tweets is a commercial app that enables you to delete all of your tweets at once.
HootSuite - Enhance your social media management with Hootsuite, the leading social media dashboard. Manage multiple networks and profiles and measure your campaign results.