Star Trek Online - Star Trek Online (STO) is a free to play MMORPG that takes place inside the Star Trek world.
FTL: Faster Than Light - FTL is a spaceship simulation roguelike-like.
X3: Terran Conflict - X3: Terran Conflict is part of the X number of video games.
ASCIILL - Third-person action puzzle game with the crazy retro style.
EVE Online - Player-created empires, player-driven markets, and endless ways to embark on your personal sci-fi adventure.
Galactic Crew - Galactic Crew is a roguelike sci-fi exploration game.