Endless Space - Endless Space is an Amazing, Strategy, Science-fiction, Turn-based, Space, Futuristic, Exploration, Co-op, Single and Multiplayer Space Simulation created and published by Amplitude Studios.
Wing Commander: Privateer - Wing Commander: Privateer is a space simulator and adventure game that allows you to build your own story in this dog eat dog universe.
Sins Of A Solar Empire - Sins of a Solar Empire is an Adventure, Strategy, Real-time-strategy, Science-fiction, Exploration, Aliens, Single and Multiplayer Space Simulation developed by Ironclad Games and published by Stardock.
DarkStar One - DarkStar One is targeted on space trading and combat.
Homeworld - Homeworld is an Action-Adventure, Science-fiction, Real-time Strategy, Real-time-tactical, Single and Multiplayer Space Simulation created by Relic Entertainment and published by Sierra Entertainment.
Star Trek Online - Star Trek Online (STO) is a free to play MMORPG that takes place inside the Star Trek world.