Keysmith - Create custom keyboard shortcuts for your Mac and the web
iCanHazShortcut - Simple shortcut manager for OS X 10.8 or higher.
Alfred - Alfred is an award-winning app for macOS which boosts your efficiency with hotkeys, keywords, text expansion and more. Search your Mac and the web, and be more productive with custom actions to control your Mac.
Quicksilver - Quicksilver is a fast and free Mac OS X productivity application that gives you the power to control your Mac quickly and elegantly. Quicksilver learns your habits, making your everyday chores simple and efficient.
Apptivate - A simple, beautiful hotkey manager.
Spark (Hotkey Manager) - Spark is a powerful and easy shortcuts manager.