What are some alternatives?
Vue.js - Reactive Components for Modern Web Interfaces
AngularJS - AngularJS lets you extend HTML vocabulary for your application. The resulting environment is extraordinarily expressive, readable, and quick to develop.
Backbone.js - Give your JS App some Backbone with Models, Views, Collections, and Events
ExpressJS - Sinatra inspired web development framework for node.js -- insanely fast, flexible, and simple
Aurelia - Next gen JS framework written with ES6 and ES7. Integrates with Web Components. No external dependencies except polyfills.