Texture Studio - Texture Studio is all you need to produce professional quality textures for use in games and tiled...
Material Maker - Cross-platform, procedural texture generation tool.
Pixen - Pixen is a professional pixel art editor designed for working with low-resolution raster art, such as those 8-bit sprites found in old-school video games.
NeoTextureEdit - NeoTextureEdit is an open source (GNU LGPL v.
TextureLab - Free, Cross-Platform, GPU-Accelerated Procedural Texture Generator.
Aseprite - Aseprite is an art program dedicated to the creation of pixel art.