TwistedBrush Pro Studio - A powerful and unique natural media painting program.
Krita - Krita is a professional FREE and open source painting program. It is made by artists that want to seaffordable art tools for everyone. Concept art. texture and matte painters, illustrations and comics.
Adobe Sketch - Adobe Sketch lets users create expressive drawings anywhere using natural drawing tools like pencils, pens, markers and watercolour brushes.
Artrage - A simple but lovely natural media painting and sketching program.
Corel Painter - Corel Painter is media painting software.
Procreate - Procreate is the most powerful and intuitive digital illustration App available for iPad®.