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Maxima - Maxima is a fairly complete computer algebra system written in Lisp with an emphasis on symbolic computation.
Wolfram Mathematica - Mathematica has characterized the cutting edge in specialized processing—and gave the chief calculation environment to a large number of pioneers, instructors, understudies, and others around the globe.
MATLAB - A high-level language and interactive environment for numerical computation, visualization, and programming
QtOctave - QtOctave: a front-end for Octave/un Front-End para Octave
SMath Studio - Tiny, powerful, free mathematical program with WYSIWYG editor and complete units of measurements support.
FriCAS - FriCAS is the name of an advanced and professional level of computer algebra system for the mathematicians, scientists, and engineers.