Autodesk ArtCAM - ArtCAM is a cad/cam software program thats been designed for artisans instead of engineers.
Vectric Aspire - The complete software solution for CNC Routing,
Mastercam - Mastercam's Dynamic Milling is a game changer for us.
SprutCAM - SprutCAM all-in-one software for CNC machines programming
PyCAM - PyCAM is a toolpath generator for 3-axis CNC machining.
LinuxCNC (the Enhanced Machine Control) - LinuxCNC: an open source CNC machine controller. It can drive milling machines, lathes, 3d printers, laser cutters, plasma cutters, robot arms, hexapods, and more.