PostCSS - Increase code readability. Add vendor prefixes to CSS rules using values from Can I Use. Autoprefixer will use the data based on current browser popularity and property support to apply prefixes for you.
CSS Peeper - Smart CSS viewer tailored for Designers.
Sass - Syntatically Awesome Style Sheets
Tailwind CSS - A utility-first CSS framework for rapidly building custom user interfaces.
Stylus - EXPRESSIVE, DYNAMIC, ROBUST CSS
Purgecss - Easily remove unused CSS