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Cheat Engine - Cheat Engine is an open source memory scanner/hex editor/debugger for Windows.
WeMod - Personalize your gaming experience Thousands of free mods and trainers for your favorite single-player PC games — all in one place.
scanmem & GameConqueror - GameConqueror is a GUI for scanmem.
GameCopyWorld - An index for Game Backup Instructions, No CD Patches, and Game Trainers
ArtMoney - Forget about cheat codes, no more cheat codes, Universal Memory Editor.
GamePatchPlanet - GamePatchPlanet allows you to browse from a huge library of PC Cheat Codes, Tweaks, and Fixes, Trainers, Tools, Gaming news, Patches and download them for free.