Oculus Medium - Sculpt, model and paint in virtual reality on a 3D canvas.
Unity - The multiplatform game creation tools for everyone.
Tilt Brush - Paint in spaces around you with Virtual Reality
Godot Engine - Feature-packed 2D and 3D open source game engine.
MasterpieceVR - Powerful VR sculpting & painting tool
Blender - Blender is the open source, cross platform suite of tools for 3D creation.