EssentialPIM - EssentialPIM is a free Personal Information Manager that keeps up with the times and lets you manage appointments, tasks, notes, contacts, password entries and email messages across multiple devices and cloud applications.
Thunderbird - Thunderbird is a free email application that's easy to set up and customize - and it's loaded with great features!
Todo.txt - Track your tasks and projects in a plain text file, todo.txt. A todo.
Microsoft Outlook - Organize your world. Outlook’s email and calendar tools help you communicate, stay on top of what matters, and get things done.
Bitrix24 - Bitrix24 is a free (for small businesses) social enterprise platform. It is a united work space which handles the many aspects of daily operations and tasks. Create your own social intranet in minutes!
eM Client - eM Client is a fully-featured email client for Windows and macOS with a clean and easy-to-use interface. eM Client also offers features for calendars, tasks, contacts, notes, and chat.