Protopage - The best iGoogle alternative. Chris Pirillo calls Protopage "The best designed".
Minimo - An elegant, simplified new tab page
Netvibes - First personalized dashboard publishing platform for the Web. Digital life managment, Widget distribution services and brand observation rooms.
Mustsee - Discover the world’s most beautiful places
Domostra.com - Place your favorite link, RSS, weather, notes and a lot of other widgets on your homepage.
New Tab by Flickr - Get a beautiful photo each time you open a new tab