React Desktop - React Desktop is a JavaScript library built on top of Facebook's React library, which aims to bring a native desktop experience to the web.
Unity - The multiplatform game creation tools for everyone.
Electron - Build cross platform desktop apps with web technologies
Godot Engine - Feature-packed 2D and 3D open source game engine.
Electron.NET - Build cross platform desktop apps with .NET Core
Blender - Blender is the open source, cross platform suite of tools for 3D creation.