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LinuxCNC (the Enhanced Machine Control) - LinuxCNC: an open source CNC machine controller. It can drive milling machines, lathes, 3d printers, laser cutters, plasma cutters, robot arms, hexapods, and more.
Inventor - Inventor is a 3D CAD software that lets you quickly create 3D models with embedded intelligence, intuitive workflows, and optimized performance.
Mach3 - Mach3 is very popular among the Hobby CNC community.
Ayam - Ayam is a free 3D modelling environment for the RenderMan interface, distributed under the BSD...
PyCAM - PyCAM is a toolpath generator for 3-axis CNC machining.
SolidWorks Simulation - Simulation solutions for SOLIDWORKS® provide an easy-to-use portfolio of analysis tools for predicting a product’s real-world physical behavior by virtually testing CAD models.