Unreal Engine - Unreal Engine 4 is a suite of integrated tools for game developers to design and build games, simulations, and visualizations.
Unity - The multiplatform game creation tools for everyone.
Godot Engine - Feature-packed 2D and 3D open source game engine.
Blender - Blender is the open source, cross platform suite of tools for 3D creation.
Phaser - Desktop and Mobile HTML5 game framework. A fast, free and fun open source framework for Canvas and WebGL powered browser games.
Stencyl - Make iOS (iPhone/iPad), Android, Flash, Windows & Mac games without code using Stencyl.