Home-Assistant.io - Home Assistant is an open-source home automation platform running on Python 3.
Gladys - An open-source home assistant powered by a Raspberry Pi 🗣️
Google Home - Set up, manage, and control your Chromecast, Chromecast Audio and Google Home devices.
SmartRent - Smart home automation for property managers and renters
ioBroker - flexible and modular application for the IoT and Smarthome
openHAB - "empowering the smart home" - vendor and technology agnostic open source home automation