Blender - Blender is the open source, cross platform suite of tools for 3D creation.
AnyLogic - AnyLogic has changed simulation modeling and expanded its application into complex business environments. The unmatched flexibility of multimethod modeling allows users to capture the complexity of virtually any system, at any level of detail.
FreeCAD - An open-source parametric 3D modeler
FlexSim - Simulation software to model, simulate, predict, and visualize systems in manufacturing, material handling, healthcare, warehousing, mining, etc.
MATLAB - A high-level language and interactive environment for numerical computation, visualization, and programming
Simio - Facility design simulation & production scheduling