Blender - Blender is the open source, cross platform suite of tools for 3D creation.
MATLAB - A high-level language and interactive environment for numerical computation, visualization, and programming
FreeCAD - An open-source parametric 3D modeler
AnyLogic - AnyLogic has changed simulation modeling and expanded its application into complex business environments. The unmatched flexibility of multimethod modeling allows users to capture the complexity of virtually any system, at any level of detail.
Wolfram Mathematica - Mathematica has characterized the cutting edge in specialized processing—and gave the chief calculation environment to a large number of pioneers, instructors, understudies, and others around the globe.
Inventor - Inventor is a 3D CAD software that lets you quickly create 3D models with embedded intelligence, intuitive workflows, and optimized performance.