CanJS - CanJS is a JavaScript library that makes developing complex applications simple and fast.
ExpressJS - Sinatra inspired web development framework for node.js -- insanely fast, flexible, and simple
Ractive.js - Ractive.js is different.
Backbone.js - Give your JS App some Backbone with Models, Views, Collections, and Events
AngularJS - AngularJS lets you extend HTML vocabulary for your application. The resulting environment is extraordinarily expressive, readable, and quick to develop.
FeathersJS - Wow your users. Build incredible real-time applications in record time.