WinCDEmu - WinCDEmu is an open-source CD/DVD/BD emulator.
ImgBurn - What in the Heck is IMG Burn? We all need to copy discs from time to time.
DAEMON Tools - The most personal application for disc imaging yet.
CDBurnerXP - Free CD, DVD, ISO, HD-DVD and Blu-Ray burning software with multi-language interface. Everyone, even companies, can use it for free.
Virtual CloneDrive - Virtual CloneDrive works and behaves just like a physical CD/DVD/Blu-ray drive, although it only exists virtually.
Brasero - Brasero is an application to burn CD/DVD for the Gnome Desktop.