pixeldudesmaker - Simple, web-based pixel art character generator.
Blender - Blender is the open source, cross platform suite of tools for 3D creation.
RPG Character Builder - Create thousands of unique character sprites for your 2D game project - free!
ZBrush - ZBrush is a digital sculpting and painting software solution.
Game Character Hub - helper program for game design (RPG Maker XP/VX and more)
Cinema 4D - Cinema 4D is a 3D modeling, animation, motion graphics and rendering application.