Game Character Hub - helper program for game design (RPG Maker XP/VX and more)
Blender - Blender is the open source, cross platform suite of tools for 3D creation.
pixeldudesmaker - Simple, web-based pixel art character generator.
Autodesk 3DS Max - 3ds Max is software for 3D modeling, animation, rendering, and visualization. Create stunning game enrivonments, design visualizations, and virtual reality experiences.
RPG Character Builder - Create thousands of unique character sprites for your 2D game project - free!
ZBrush - ZBrush is a digital sculpting and painting software solution.