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Odesi - ODESI is a music sketchpad that exports your projects to Audio and MIDI.
Reaper - Reaper is a focused digital audio workstation (DAW) developed by Cockos. In the creation of the software, the digital audio technology company intended to make audio editing accessible to the masses.
Helio Workstation - Cross-platform lightweight speed-painting tool for creating music.
Audacity - Audacity is a free and open-source audio production software suite that includes a surprising array of editing tools and recording systems.
RapidComposer - MusicDevelopments RapidComposer: Music Prototyping and Automated Composition Software
Ardour - Record, edit, and mix on Linux, Mac OS X, and Windows.