NTLite - The Ultimate Windows Customization Tool
Tron Script - Tron is a glorified collection of batch files that automate the process of cleaning up Windows systems.
Win Toolkit - BUGS: Do not post bugs in the comments.
SKTools - SKTools is a multi-featured and easy-to-use application that is bundled with over 60 tools to help you boost the performance of the system.
Ultimate Windows Tweaker - Ultimate Windows Tweaker is a freeware Tweak UI Utility for tweaking and optimizing Windows.
NETGATE Registry Cleaner - NETGATE Registry Cleaner cleans and defragment your registry.