Godot Engine - Feature-packed 2D and 3D open source game engine.
Inkscape - Inkscape is a free, open source professional vector graphics editor for Windows, Mac OS X and Linux.
Unity - The multiplatform game creation tools for everyone.
Sketch - Professional digital design for Mac.
Unreal Engine - Unreal Engine 4 is a suite of integrated tools for game developers to design and build games, simulations, and visualizations.
Affinity Designer - Professional creative software, exclusively for Mac.